Phytochemicals; Targeted-Based Therapeutic Approaches for Pigmentation Disorders

Skin pigmentation disorders refer to conditions that affect the color of skin due alterations in production or distribution melanin, pigment responsible for color. The development is a complex process involving various signaling pathways, including melanin synthesis pathway, cyclic AMP and Wnt pathway. Dysregulation these pathways can lead disorders. Phytotherapeutic approaches have been increasingly studied as potential treatment This literature review aimed describe basic mechanism melanogenesis, involved formation, certain diseases their through plant extracts. Plant extracts containing bioactive compounds such flavonoids, phenolic acids, tannins shown anti-pigmentary effects mechanisms, inhibition tyrosinase activity, reduction synthesis, modulation melanogenesis-related pathways. are multifactorial significantly impact person's quality life. Targeting regulation, particularly phytotherapeutic approaches, represents promising avenue new therapies